Autoantibody Profiling
- Pan J et al. (2020) Integration Of IgA and IgG Autoantigens Improves Performance Of Biomarker Panels For Early Diagnosis Of Lung Cancer Mol Cell Proteomics, 19(3):490-500
- Ling HZ et al. (2020) Discovery of new serum biomarker panels for systemic lupus erythematosus diagnosis Rheumatology, 59(6):1416-1425
- Dhande IS et al. (2019) Germ-line genetic variation in the immunoglobulin heavy chain creates stroke susceptibility in the spontaneously hypertensive rat Physiol Genomics 51(11):578-585.
- Fan W et al. (2019) Sa1679–Multiple rather than specific Antibodies were identified in Irritable Bowel Syndrome using Huprot Microarray Approach Gastroenterology 156 (6), Supplement 1, Page S-364
- Lastwika KJ et al. (2019) Tumor-derived autoantibodies identify malignant pulmonary nodules. Am J Respir Crit Care Med, 199 (10)
- Ye S et al. (2019) Plasma proteomic and autoantibody profiles reveal the proteomic characteristics involved in longevity families in Bama, China Clin Proteomics, 16:22
- Gowen MF et al. (2018) Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors. J. Transl. Med., 16(1):82
- Bigley V et al. (2018) Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation. J. Allergy Clin Immunol, 141(6):2234-2248
- Bremer HD et al. (2018) ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease Sci.Rep. 8(1):4852
- Chung JM et al. (2018) Identification of the thioredoxin-Like 2 Autoantibody as a Specific Biomarker for Triple-Negative Breast Cancer. J Breast Cancer 21:87-90
- Pan J et al. (2017) Identification of Serological Biomarkers for Early Diagnosis of Lung Cancer Using a Protein Array-Based Approach. Mol Cell Proteomics 16 (12):2069-2078
- Wang J et al. (2017) PTMA, a new identified autoantigen for oral submucous fibrosis, regulates oral submucous fibroblast proliferation and extracellular matrix. Oncotarget. 8(43): 74806–74819.
- Gupta S et al. (2017) Serum Profiling for Identification of Autoantibody Signatures in Diseases Using Protein Microarrays. Methods Mol Biol 1619:303-315.
- Gupta S et al. (2017) Evaluation of autoantibody signatures in meningioma patients using human proteome arrays. Oncotarget 8 (35): 58443-58456
- Chung et al. (2017) Phenotyping and auto-antibody production by liver-infiltrating B cells in primary sclerosing cholangitis and primary biliary cholangitis J. Autoimmun 77:45-54
- Ogishi et al. (2016) Delineation of autoantibody repertoire through differential proteogenomics in hepatitis C virus-induced cryoglobulinemia. Sci Rep 6:29532.
- Yang L et al. (2016) Identification of serum biomarkers for gastric cancer diagnosis using a human proteome microarray. Mol Cell Proteomics 15(2):614-23.
- Fiorentino DF et al. (2016) PUF60: a prominent new target of the autoimmune response in dermatomyositis and Sjögren’s syndrome. Ann Rheum Dis 75(6): 1145–1151.
- Hu CJ et al. (2016) Identification of Novel Biomarkers for Behcet Disease Diagnosis Using HuProt Array Approach. Mol Cell Proteomics 16(2):147-156
- Shi L et al. (2016) Application of high-throughput protein array in clinical screening for tumor markers. Int J Clin Exp Med 9:8529-8535.
- Syed P et al. (2015) Autoantibody profiling of glioma serum samples to identify biomarkers using human proteome arrays Sci Rep 15(5):13895
- Hu C et al. (2015) Autoantibody profiling on human proteome microarray for biomarker discovery in cerebrospinal fluid and sera of neuropsychiatric lupus. PLoS One 10(5):e0126643
- Hu CJ et al. (2012). Identification of new autoantigens for primary biliary cirrhosis using human proteome microarrays. Mol Cell Proteomics 11(9):669-80.
Antibody Specificity and Crossreactivity
- Venkataraman A et al. (2018) A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors. Nat Methods, 15(5):330-338
- Ramos-López et al. (2018) Antibody Specificity Profiling using Protein Microarrays. In: Rockberg J., Nilvebrant J. (eds) Epitope Mapping Protocols, Methods in Molecular Biology, vol 1785, 223-229
- Washburn N et al. (2017) High-resolution physicochemical characterization of different intravenous immunoglobulin products. PLoS One 12(7):e018125
- Sterner E et al. (2017) Therapeutic Antibodies to Ganglioside GD2 Evolved from Highly Selective Germline Antibodies. Cell Rep 20(7):1681-1691
- Kim YP et al (2014) Effective Therapeutic Approach for Head and Neck Cancer by an Engineered Minibody Targeting the EGFR Receptor. PLoS One. 1;9(12):e113442.
- Liu S et al. (2014) Characterization of monoclonal antibody's binding kinetics using oblique-incidence reflectivity difference approach. MAbs 7:110-119
- Jeong JS et al. (2012) Rapid identification of monospecific monoclonal antibodies using a human proteome microarray. Mol Cell Proteomics 11(6):O111.016253
Protein Interactomics
- Yue H et al. (2019) Calpastatin participates in the regulation of cell migration in BAP1-deficient uveal melanoma cells Int J Opthalmol 12(11):1680-1687.
- Zhao T et al. (2019) DNA methylation-regulated QPCT promotes sunitinib resistance by increasing HRAS stability in renal cell carcinoma Theranostics; 9(21): 6175–6190
- Song G et al. (2019) Proteome-wide Tyrosine Phosphorylation Analysis Reveals Dysregulated Signaling Pathways in Ovarian Tumors. Mol Cell Proteomics. 18(3):448-460.
- Cao T et al. (2019) A Two-Way Proteome Microarray Strategy to Identify Novel Mycobacterium tuberculosis-Human Interactors. Front. Cell. Infect. Microbiol, 28;9:65
- Cho HM et al. (2019) Drp1-Zip1 Interaction Regulates Mitochondrial Quality Surveillance System Mol Cell. 73(2):364-376.e8
- Wu FL et al. (2018) Global profiling of PknG interactions using a human proteome microarray reveals novel connections with CypA. Proteomics, 18(23):e1800265
- Feng Y et al. (2018) High-Throughput Chip Assay for Investigating Escherichia coli Interaction with the Blood-Brain Barrier Using Microbial and Human Proteome Microarrays (Dual-Microarray Technology) Anal Chem 90(18):10958-10966
- Guo G et al. (2018) The cytomegalovirus protein US31 induces inflammation through mono-macrophages in systemic lupus erythematosus by promoting NF-κB2 activation. Cell Death Dis 24(9):2
- Choi S et al (2018) PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation. Mol Cell. 70(5):920-935.e7.
- Bao Y et al (2018) Angiopoietin-like protein 3 blocks nuclear import of FAK and contributes to sorafenib response. Br J Cancer. 119(4):450-461.
- Yang Z et al. (2017) A Human Proteome Array Approach to Identifying Key Host Proteins Targeted by Toxoplasma Kinase ROP18. Mol Cell Proteomics 16:469-484
- Cox E et al. (2017) Global Analysis of SUMO-Binding Proteins Identifies SUMOylation as a Key Regulator of the INO80 Chromatin Remodeling Complex. Mol Cell Proteomics 16:812-23
- Liu M et al. (2017) Disruption of Ssp411 causes impaired sperm head formation and male sterility in mice. Biochim Biophys Acta Gen Subj. 1862(3):660-668.
- Li H et al. (2016) Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier. Genetics 203(2):763-70
- Wang Y et al. (2016) A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1. Science 354 (6308)
- Ainscough J et al. (2015) Interleukin-1β Processing Is Dependent on a Calcium-mediated Interaction with Calmodulin. J. Biol. Chem. 290(52):31151-61
- Hu J et al. (2015) Systematic prediction of scaffold proteins reveals new design principles in scaffold-mediated signal transduction. PLoS Comput Biol 11(9):e1004508
- Jung JG et al. (2014) Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer. PLos Genet 10:e1004751.
- Ma TM et al. (2014) Serine racemase regulated by binding to stargazin and PSD-95: Potential NMDA-AMPA glutamate neurotransmission cross-talk. J Biol Chem. 289(43):29631-41
- Deng, RP et al. (2014) Global Identification of O-GlcNAc Transferase (OGT) Interactors by a Human Proteome Microarray and the Construction of an OGT Interactome. Proteomics 14:1020-30.
- Fan, Q et al. (2014) Identification of proteins that interact with alpha A-crystallin using a human proteome microarray. Mol Vis 20:117-124.
- Chen Y et al. (2013) Bcl2-associated Athanogene 3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity. Mol Cell Proteomics 12(10):2804-19.
- Huang Y. et al (2012) Global tumor protein p53/p63 interactome: making a case for cisplatin chemoresistance. Cell Cycle 11(12):2367-79.
Kinase Assays
- Hu J et al. (2015) Systematic prediction of scaffold proteins reveals new design principles in scaffold-mediated signal transduction. PLoS Comput Biol 11(9):e1004508
- Tarrant MK et al. (2012) Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis. Nat Chem Biol 8(3):262-9.
Other Enzyme Assays
- Uzoma I et al. (2018) Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk between SUMOylation and Phosphorylation Promotes Cell Migration. Mol. Cell. Proteomics 17(5):871-888
- Xu Z et al. (2017) Systematic identification of the protein substrates of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-T1/T2/T3 using a human proteome microarray. Proteomics 17:11
- Cox E et al. (2015) Identification of SUMO E3 ligase-specific substrates using the HuProt human proteome microarray. Methods Mol Biol. 1295:455-63
- Lee YI et al. (2013) Protein microarray characterization of the S-nitrosoproteome. Mol Cell Proteomics 13:63-72.
Nucleic Acid Binding
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Yu B et al. (2020) A Novel LncRNA, AC091729.7 Promotes Sinonasal Squamous Cell Carcinomas Proliferation and Invasion Through Binding SRSF2 Front. Oncol 9;1575
- Kang CL et al. (2019) LncRNA AY promotes hepatocellular carcinoma metastasis by stimulating ITGAV transcription Theranostics 9(15):4421-4436
- Liu L et al. (2019) Insight into novel RNA-binding activities via large-scale analysis of lncRNA-bound proteome and IDH1-bound transcriptome. Nucleic Acid Res. 47(5):2244-2262
- McClymont et al. (2018) Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons. Am J Hum Genet 103(6):874-892
- Qin M et al. (2018) Circ-UBR5: An exonic circular RNA and novel small nuclear RNA involved in RNA splicing. Biochem Biophys Res Comm 503 (2):1027-1034.
- Wang Y et al. (2018) HIC1 deletion promotes breast cancer progression by activating tumor cell/fibroblast crosstalk. J Clin Invest. 128(12):5235-5250.
- Barry G et al. (2017) The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states. Sci Rep 7:40127
- Barry G et al. (2014) The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing. Molec Psychiatry. 19(4):486-94.
- Donnelly CJ et al. (2013) RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. Neuron 80(2):415-28.
- Fan B et al. (2013) A human proteome microarray identifies that the heterogeneous nuclear ribonucleoprotein K (hnRNP K) recognizes the 5' terminal sequence of the hepatitis C virus RNA. Mol Cell Proteomics. 13(1):84-92.
- Hu S. et al (2009) Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling. Cell. 139(3):610-22.
Small Molecule Profiling
- Jia D et al (2019) Cardioprotective mechanism study of salvianic acid A sodium based on a proteome microarray approach and metabolomic profiling of rat serum Mol. Omics 2019 15(4):271-279.
- Zhang HN et al (2015) Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic. Proc Natl Acad Sci U.S.A. 112 (49):15084-9
Other
- Syu GD (2019) Development and application of a high-content virion display human GPCR array. Nature Communications 10: 1997
- Coll JM (2018) Herpesvirus infection induces both specific and heterologous antiviral antibodies in carp. Front Immunol. 9(39)
- Azevedo C (2018) Screening a Protein Array with synthetic biotinylated Inorganic Polyphosphate to define the human PolyP-ome. ACS Chem Biol. 13 (8):1958-1963
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