CPA

Research and development of protein arrays and their applications in proteomics

+44 (0)1223 496557

info@cambridgeproteinarrays.com

MENU menu

Close close menu

Protein Small Molecule Interactions

 

HuProt™ application: Protein-small molecule interactions

 

Explore interaction profiles and identify off-target binding.

 

HuProt™ arrays can also be employed to determine near proteome-wide interaction profiles of small molecules, such as drug candidates. The microarray allows the rapid generation of binding profiles. 

 

Assay Format


Read-out of the HuProt microarrays is by fluorescence, hence a fluorescent label needs to be conferred on the small molecule of interest. Options include:

 

 

Reference

 

Zhang HN et al (2015).  Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic. Proc Natl Acad Sci U.S.A112(49):15084-9

GET IN TOUCH

 

Please contact us to discuss setup requirements for your small molecule of interest.

 

+44 (0)1223 496557

info@cambridgeproteinarrays.com