Research and development of protein arrays and their applications in proteomics

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Protein Small Molecule Interactions


HuProt™ application: Protein-small molecule interactions


Explore interaction profiles and identify off-target binding.


HuProt™ arrays can also be employed to determine near proteome-wide interaction profiles of small molecules, such as drug candidates. The microarray allows the rapid generation of binding profiles. 


Assay Format

Read-out of the HuProt microarrays is by fluorescence, hence a fluorescent label needs to be conferred on the small molecule of interest. Options include:





Zhang HN et al (2015).  Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic. Proc Natl Acad Sci U.S.A112(49):15084-9



Please contact us to discuss setup requirements for your small molecule of interest.


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