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Research and development of protein arrays and their applications in proteomics

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Protein Interactomics

 

HuProt™ application: Protein-protein interactions

Determine the interactome of your favourite protein

 

HuProt™ arrays provide a platform for screening proteins for binary interactions with the world's largest collection of human proteins immobilised on a single microarray.  Over 19,000 potential interactions are assessed in a single experiment. Compared to pulldown methods detecting endogenous interaction partners, the potential interaction partners are present on the array in less diverse protein concentrations. This facilitates detection of those interactors with low abundance in the cellular system. 

 

Assay Format


Read-out of the HuProt microarrays is by fluorescence, hence a fluorescent label needs to be conferred on the protein of interest. Options include:

 

 

References

 

GET IN TOUCH

 

Contact us to discuss how your screening project can benefit from using HuProt v3.1 arrays or the set up options for your protein.

 

+44 (0)1223 496557

info@cambridgeproteinarrays.com